Brain & NeuroscienceResearch
Understanding the Links Between Autism, Epilepsy, and Co-Occurring Conditions
Research explores why some autistic individuals experience epilepsy, gastrointestinal differences, and anxiety—and how these conditions interact across the lifespan.
Epilepsy and Autism
Epilepsy occurs in approximately 20-30% of autistic individuals in clinical samples, with lower rates in population studies, according to a 2022 review in Epilepsy & Behavior. Shared neurological factors may contribute to this overlap, though environmental influences and diagnostic timing also play roles, as noted in ASAN’s 2024 response to the IACC.
Gastrointestinal Patterns and Behavior
Some autistic individuals report gastrointestinal (GI) differences, with a 2019 study in Autism Research observing correlations between GI symptoms and repetitive behaviors. While the gut-brain axis is an area of active study, the Autism Spectrum News 2023 article cautions against oversimplifying these complex interactions.
The NIH’s 2025 workshop on neurodevelopmental disorders highlights the need for further research in this area.
Mental Health Across the Lifespan
Psychiatric conditions like anxiety (28.5%) and ADHD (19.8%) are more commonly diagnosed among autistic adults, per a 2022 Psychological Medicine study. The Autism Research Institute notes that tailored support strategies can help address these needs.
Physical Health Considerations
A 2023 University of Cambridge study found higher rates of some physical health conditions among autistic individuals, though the reasons—whether biological, environmental, or related to healthcare access—remain unclear. The NIH’s 2025 workshop on neurodevelopmental disorders highlights the need for further research in this area.
Sources
- 01Co-occurring conditions in autistic teens increase with age
- 02Autistic individuals have increased risk of chronic physical health conditions across the whole body
- 03Neurological and psychiatric disorders among autistic adults: a population healthcare record study
- 04Characterizing the Interplay Between Autism Spectrum Disorder and ...
- 05Prevalence of co-occurring conditions in children and adults with ...
- 06Autism Spectrum Disorder and Epilepsy: Pathogenetic Mechanisms ...
- 07Study examines factors associated with co-occurrence of autism and ...
Common questions
Behind the brief
Adversarial editorial review
Open thread